- Product Details
Keywords
- Cholesterol
- zetia
- Rosuvastatin
Quick Details
- ProName: Crestor Zetia
- CasNo: 287714-41-4
- Appearance: Solid white
- Application: Oral in take
- DeliveryTime: Express delivery
- PackAge: Descrete packaging with aluminum foil
- Port: Borispol
- ProductionCapacity: Metric Ton/Day
- Purity: >98%
- Storage: Store at room temperature
- Transportation: Air
- LimitNum: 0 Metric Ton
Superiority
Rosuvastatin is a statin with antilipidemic and potential antineoplastic activities. Rosuvastatin selectively and competitively binds to and inhibits hepatic hydroxymethyl-glutaryl coenzyme A (HMG-CoA) reductase, the enzyme which catalyzes the conversion of HMG-CoA to mevalonate, a precursor of cholesterol. This leads to a decrease in hepatic cholesterol levels and increase in uptake of LDL cholesterol. In addition, rosuvastatin, like other statins, exhibits pro-apoptotic, growth inhibitory, and pro-differentiation activities in a variety of tumor cell types; these antineoplastic activities may be due, in part, to inhibition of the isoprenylation of Ras and Rho GTPases and related signaling cascades.